Cursed

“Beware the full moon.”

Ellie (Christina Ricci) is an orphan in Los Angeles who looks after her teenage brother Jimmy (Jesse Eisenberg) and keeps a tight grip on both their lives. A night drive ends with a werewolf attack on the two of them and a third stranger, and the bites leave all three changed. Wes Craven sends them after the creature that started it, since a curse like this only ends when its source does.