Splice
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Splice

(2010)Directed by Vincenzo Natali104 min · RHorror, Science Fiction
“She's not human...not entirely.”

Elsa Kast (Sarah Polley) and Clive Nicoli (Adrien Brody) are young, rebellious scientists who want to push their gene-splicing work past what the law allows. They add human DNA to their animal samples, and what grows from it is Dren (Delphine Chanéac), who develops from a deformed infant into a winged human-chimera. Vincenzo Natali keeps the focus on the couple, who raise her in secret and have no idea what they have taken on.

Adrien Brodyas Clive Nicoli
Sarah Polleyas Elsa Kast
Brandon McGibbonas Gavin Nicoli
Simona Măicănescuas Joan Chorot
David Hewlettas William Barlow
Abigail Chuas Child Dren
Doug Hictonas Lab tech (uncredited)